Our Published Research

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“We do not stand on the sidelines. We are in the field, working with researchers to make real progress for patients.”

— Lynn Matrisian, PhD, MBA,
Chief Science Officer, Pancreatic Cancer Action Network

As part of our strategic approach to improve outcomes for pancreatic cancer patients, our Scientific and Medical Affairs team conducts independent and collaborative research. We disseminate important findings through prestigious journal publications, posters and presentations at international meetings. As a result, we are unifying and activating the research community with the urgency and passion to drive progress and improve patients’ lives around the world.

Our Cancer Research article was the journal’s most cited article in 2014 and continues to be referenced in major publications today.

Data published in Lancet Oncology in 2020 showed that PanCAN’s Know Your Tumor® precision medicine service can help pancreatic cancer patients live longer. The results showed, for the first time, that patients who are able to go on therapies that match their tumor biology live an average of one year longer compared to patients who don’t.

Research conducted by PanCAN’s Scientific and Medical Affairs team is shining a light on the needs of patients and caregivers to shape a brighter future. We are also learning from past efforts to ensure that the field evolves. In doing so, we are holding ourselves and our public and private partners accountable to progress.

We are asking big questions that might otherwise go unaddressed without trusted voices like  PanCAN actively participating in research.

 

Explore Our Research

Improving Clinical Trials

Evaluation of Pancreatic Cancer Clinical Trials and Benchmarks for Clinically Meaningful Future Trials: A Systematic Review
JAMA Oncology, 2016.

The Past, Present, and Future of Pancreatic Cancer Clinical Trials
American Society of Clinical Oncology Educational Book, 2016.

Pancreatic Cancer Clinical Trials and Accrual in the United States
Journal of Clinical Oncology, 2013.

Increasing Survival

Private Funding for Pancreatic Cancer Research: More Than a Chip Shot.
Gastroenterology, 2017.

Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
Cancer Research, 2014.

Understanding Patient and Caregiver Priorities

Frequency of Appropriate Use of Pancreatic Enzyme Replacement Therapy and Symptomatic Response in Pancreatic Cancer Patients
Pancreas, 2019

Pancreas Cancer-Associated Weight Loss
The Oncologist, 2018

Patient and caregiver awareness of pancreatic cancer treatments and clinical trials
Gastrointestinal Oncology, 2016.

Pancreatic cancer: Patient and caregiver perceptions on diagnosis, psychological impact, and importance of support
Pancreatology, 2015.

Molecular Profiling with Know Your Tumor®

Overall survival in patients with pancreatic cancer receiving matched therapies following molecular profiling: a retrospective analysis of the Know Your Tumor registry trial
Lancet Oncology, 2020.

Outcomes in Patients With Pancreatic Adenocarcinoma With Genetic Mutations in DNA Damage Response Pathways: Results From the Know Your Tumor
Journal of Clinical Oncology Precision Oncology, 2019.

Molecular Profiling of Pancreatic Cancer Patients: Initial Results from the Know Your Tumor Initiative
Clinical Cancer Research, 2018.

Identification of a novel metabolic-related mutation (IDH1) in metastatic pancreatic cancer
Cancer Biology & Therapy, 2016.

A pilot study evaluating concordance between blood-based and patient-matched tumor molecular testing within pancreatic cancer patients participating in the Know Your Tumor (KYT) initiative
Oncotarget, 2016.

Meet Our Scientific and Medical Leadership

  • Lynn Matrisian, PhD, MBA

  • Chief Science Officer

  • Sudheer Doss, PhD

  • Chief Data Officer

With generous partners like you, we are picking up the pace of scientific and medical research. We cannot wait because patients cannot wait.
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